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STEP UP, the phase 3b trial (a large human study) that compared the two doses in 1,407 adults living with obesity, reported these sensations in: 1 22.9% of people on Wegovy 7.2 mg 6.0% of people on Wegovy 2.4 mg 0.5% of people on a placebo (1 participant out of 201) That’s close to four times as many people on 7.2 mg as on 2.4 mg, which is why this side effect has become associated with the higher dose

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When to Contact Your PlexusDx Provider About Constipation Reach out to your provider if constipation persists beyond two weeks despite hydration, fiber, and over-the-counter medications